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CoQ10, ubiquinol same nutrient, but differ in quality, brands
By SUZY COHEN Dear Pharmacist
Published: 1/17/2009 2:23 AM
Last Modified: 1/17/2009 2:34 AM
Dear Pharmacist, I have high cholesterol, hypertension and heart palpitations. I take Zocor (sim- vastatin) and read in your previous column to take CoQ10 for leg cramps related to my medicine. Then I heard you on the radio tell us to take something else, ubiquinone or ubiquinol. Are they all the same thing? — A.N., Memphis, Tenn.
Answer: They're not the same. Leg cramps and muscle pain can be the result of the drug mugging effect of statin cholesterol medicines such as Advicor, Pravachol, Zocor, Lipitor, Mevacor and others. These drugs block production of cholesterol in the liver, but that's also where CoQ10 is made. A deficiency of CoQ10 can cause liver damage, muscle weakness, leg cramps, memory loss, fatigue, shortness of breath, cardiac arrhythmias, heart attack, stroke or rhabdomyolysis (even if you have perfect cholesterol). It's not just statins though; diabetic meds, estrogen hormones, antidepressants and blood pressure meds all impact levels of CoQ10. I've posted a lengthy list of medications which suppress CoQ10 at tulsaworld.com/pharmacist.
Every living cell makes a form of CoQ10 and since the substance is so ubiquitous in nature, it is also called "ubiquinone." Product labels state ubiquinone, CoQ10 or Coenzyme Q10. These are all the same nutrient, although quality differs greatly among brands. Synthetic versions, as well as brands derived from bacteria, don't have to print this information on the label so consumers don't realize they are getting
poor-quality CoQ10.
The human body transforms CoQ10 (ubiquinone) into its active, body-ready form called "ubiquinol." This does all the work for you. Notice the OL at the end of the word. Only in the last year has Kaneka, the world's leading producer of pure CoQ10, been able to produce and stabilize ubiquinol, and it exactly matches the human body. Kaneka supplies clinical trials with their CoQ10, and most studies are positive. Since it's available, stronger, and highly usable, I recommend ubiquinol.
By SUZY COHEN Dear Pharmacist
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